Hydrogel That Could Help To Cure Damaged Nerves

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Injuries to peripheral Nerves may causes chronic pain , paralysis or major disabilities . All these may be the reason for not achieving your goal of the life .
But Scientists discovered a stretchable Conductive hydrogel . It could be used in the future for repairing these damaged nerves . They report their results in ACS nano .

Purpose For Discovering Hydrogel

Severe nerves damage or major cut in the nerve may be difficult to repair which can occur during accident . Now a days doctors use autologous method for nerves repair in which they cut a part of nerve from somewhere else in the body itself and attach it onto damaged nerve endings .

But for this reason, multiple follow up surgeries may be required which can be difficult for a person to afford .
Doctors also use artificial nerve Graft along with supporting cells which could be a life saving support but it takes a lots of time to get functional .

What is Hydrogel ?

Qun-Dong Shen, Chang-Chun Wang, Ze-Zhang Zhu and colleagues wanted to develop an effective, fast-acting treatment that could replace autologous nerve transplantation.

For this Purpose, they made a water swollen, bio compatible conductive hydrogel which could do this work efficiently .

This is tough but a stretchable polymer containing polyacrylamide and polyaniline . This is 3D microporous in which damaged nerve cells enter easily and could help to repair damaged tissue .

Experiment On Rat

First time , Chinese researcher performed this experiment on the damaged nerve part of frog . They attached hydrogel on the Damaged sciatic nerve of the frog And waited for 2 weeks only.

They find that a performance of the frog is much better than non treated frog . Conductance of the hydrogel can improve with irradiation of near infra-red light . It can easily enter into its microporous part and improve its conductance .

The authors acknowledge funding from the National Key Research and Development Program of China, the National Natural Science Foundation of China, the Program for Changjiang Scholars and Innovative Research Team in University, and Program B for Outstanding Ph.D. Candidate of Nanjing University.

Journal reference :

Mei Dong, Bo Shi, Dun Liu, Jia-Hao Liu, Di Zhao, Zheng-Hang Yu, Xiao-Quan Shen, Jia-Min Gan, Ben-long Shi, Yong Qiu, Chang-Chun Wang, Ze-Zhang Zhu, Qun-Dong Shen. Conductive Hydrogel for a Photothermal-Responsive Stretchable Artificial Nerve and Coalescing with a Damaged Peripheral NerveACS Nano, 2020; DOI: 10.1021/acsnano.0c05197

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